SKI II

Overview

SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation.

Application

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Product Information

• Catalog No.: HY-13822
• CAS No.: 312636-16-1
• Molecular Formula: C15H11ClN2OS
• Molecular Weight: 302.78
• Purity: 99.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.75 mg/mL (9.08 mM); Clear solution
• Availability: In-stock

Source

Original product source