2′,2′-Difluorodeoxyuridine

2′,2′-Difluorodeoxyuridine
  • CAS No.:114248-23-6
  • Grade:99.36%
  • Formula:C9H10F2N2O5
  • M.W.:264.18
  • Solvent:≥ 5 mg/mL (18.93 mM); Clear solution

Overview

2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine ( HY-17026 ). 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-138253
  • CAS No.: 114248-23-6
  • Molecular Formula: C9H10F2N2O5
  • Molecular Weight: 264.18
  • Purity: 99.36%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (18.93 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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