MRIA9

Overview

MRIA9, a chemical probe, is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC 50 values of 516 nM, 180 nM and 127 nM for SIK1 , SIK2 and SIK3 , respectively.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Salt-inducible Kinase (SIK) | Products > Signaling Pathways > PAK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-139253
• CAS No.: 2750707-05-0
• Molecular Formula: C24H22ClFN6O3
• Molecular Weight: 496.92
• Purity: 98.88%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 5 mg/mL (10.06 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source