2-Deoxy-D-glucose 6-phosphate

Overview

2-Deoxy-D-glucose 6-phosphate disodium is an ATP-competitive and 2-deoxy-D-glucose non-competitive Hexokinase inhibitor, with a K i value of 1.45 mM against bovine heart hexokinase . 2-Deoxy-D-glucose 6-phosphate disodium exerts ATP-competitive and 2-deoxy-D-glucose non-competitive inhibitory effects on bovine heart hexokinase . 2-DG inhibits glycolysis via the generation and intracellular accumulation of 2-Deoxy-D-glucose 6-phosphate disodium, thereby inhibiting the functions of hexokinase and Glucose-6-phosphate isomerase , and inducing cell death. 2-Deoxy-D-glucose 6-phosphate disodium can be used in cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Hexokinase | Products > Signaling Pathways > Glucose-6-Phosphate Isomerase (GPI)

Product Information

• Catalog No.: HY-139409
• CAS No.: 3573-50-0
• Molecular Formula: C6H13O8P
• Molecular Weight: 244.14
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source