α5β1 integrin agonist-1

Overview

α5β1 integrin agonist-1 is an α5β1 integrin agonist, with an EC 50 of 1.5 nM. α5β1 integrin agonist-1 inhabits α4β1 integrin (IC 50 = 2.99 μM) in Jurkat/VCAM-1 adhesion assayα5β1 integrin agonist-1 induces concentration-dependent apoptosis and activates the caspase 3/7 pathway in α5β1 integrin-expressing K562 cancer cells. α5β1 integrin agonist-1 can be used for the study of cancer .

Application

Products | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Integrin | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-139702
• CAS No.: 2756557-83-0
• Molecular Formula: C24H26FN5O9
• Molecular Weight: 547.49
• Purity: 99.67%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.57 mM); Clear solution
• Availability: In-stock

Source

Original product source