JNJ-61803534

Overview

JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC 50 of 9.6 nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation conditions.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR

Product Information

• Catalog No.: HY-139780
• CAS No.: 1917306-14-9
• Molecular Formula: C23H23Cl2F6N3O4S
• Molecular Weight: 622.41
• Purity: 99.84%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.34 mM); Clear solution
• Availability: In-stock

Source

Original product source