Chk1-IN-6

Overview

Chk1-IN-6 is a selective and orally active Chk1 inhibitor with an IC 50 of 16.1 nM. Chk1-IN-6 shows antiproliferative activity of MV-4-11 cells. Chk1-IN-6 exerts effective response in the MV-4-11 xenograft mouse model. Chk1-IN-6 exhibits synergistic anticancer effect with Gemcitabine ( HY-17026 ). Chk1-IN-6 can be used in the research of cancers such as acute myeloid leukemia and colorectal adenocarcinoma.

Application

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Product Information

• Catalog No.: HY-139901
• CAS No.: 2428423-77-0
• Molecular Formula: C16H18F3N7
• Molecular Weight: 365.36
• Purity: 98.39%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source