(S)-CCG-1423

Overview

(S)-CCG-1423 is an inhibitor of Rho signaling that blocks the nuclear import of MRTF-A . (S)-CCG-1423 reduces the nuclear accumulation of MRTF-A and improves glucose uptake and tolerance in insulin-resistance mice in vivo. (S)-CCG-1423 exhibits higher inhibition activity than the SR- and the R-isomers of CCG-1423 ( HY-13991 ). (S)-CCG-1423 can be used for the research of cancer and diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-13991A
• CAS No.: 2319939-24-5
• Molecular Formula: C18H13ClF6N2O3
• Molecular Weight: 454.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source