CSF1R-IN-3

Overview

CSF1R-IN-3 (compound 21) is a potent and orally active CSF-1R inhibitor ( IC 50 =2.1 nM). CSF1R-IN-3 is a potent antiproliferative activity against colorectal cancer cells. CSF1R-IN-3 inhibits the progression of colorectal cancer by suppressing the migration of macrophages, reprograming M2-like macrophages to the M1 phenotype, and enhancing the antitumor immunity.

Application

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Product Information

• Catalog No.: HY-139990
• CAS No.: 2760584-90-3
• Molecular Formula: C30H38N8O4
• Molecular Weight: 574.67
• Purity: 98.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source