Prucalopride

Overview

Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer .

Application

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Product Information

• Catalog No.: HY-14151
• CAS No.: 179474-81-8
• Molecular Formula: C18H26ClN3O3
• Molecular Weight: 367.87
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 50 mg/mL (135.92 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source