3-Methylthienyl-carbonyl-JNJ-7706621

Overview

3-Methylthienyl-carbonyl-JNJ-7706621 is a potent and selective inhibitor of cyclin-dependent kinase ( CDK ) , with IC 50 s of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A , respectively. 3-Methylthienyl-carbonyl-JNJ-7706621 also shows potent inhibition of GSK-3 ( IC 50 =0.041 μM) and modest potency against CDK4 , VEGF-R2 , and FGF-R2 ( IC 50 =0.11, 0.13, 0.22 μM, respectively). 3-Methylthienyl-carbonyl-JNJ-7706621 can be used for the research of cancer .

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > FGFR

Product Information

• Catalog No.: HY-141685
• CAS No.: 443798-09-2
• Molecular Formula: C14H14N6O3S2
• Molecular Weight: 378.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source