(1R,3S)-Compound E

Overview

(1R,3S)-Compound E is the isomer of Compound E ( HY-14176 ), and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC 50 s of 0.24, 0.37, 0.32 nM, respectively.

Application

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Product Information

• Catalog No.: HY-14176A
• CAS No.: 504428-17-5
• Molecular Formula: C27H24F2N4O3
• Molecular Weight: 490.50
• Purity: 99.61%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source