Compound E (GMP)

Overview

Compound E (GMP) is a GMP-grade Compound E ( HY-14176 ). GMP-grade small molecules can be used as adjuvant reagents in cell therapy. Compound E is a γ-secretase inhibitor. Compound E inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC 50 values ​​of 0.24, 0.37, and 0.32 nM, respectively.

Application

Products | Products > GMP Small Molecules | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > γ-secretase

Product Information

• Catalog No.: HY-14176G
• CAS No.: 209986-17-4
• Molecular Formula: C27H24F2N4O3
• Molecular Weight: 490.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source