SU4312

Overview

SU4312 is the racemate of (Z)-SU4312 and (E)-SU4312. (Z)-SU4312 inhibits PDGFR and FLK-1 with IC 50 s of 19.4 and 0.8 μM, respectively. (E)-SU4312 inhibits PDGFR , FLK-1, EGFR , HER-2, and IGF-1R with IC 50 s of 24.2, 5.2, 18.5, 16.9 and 10.0 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > VEGFR

Product Information

• Catalog No.: HY-100349
• CAS No.: 5812-07-7
• Molecular Formula: C17H16N2O
• Molecular Weight: 264.32
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: 2.08 mg/mL (7.87 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source