Olprinone (Loprinone) is a potent phosphodiesterase (PDE) 3 inhibitor, with IC 50 s of 150, 100, 0.35 and 14 μM for PDE1 , PDE2 , PDE3 and PDE4 , respectively. Olprinone is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity.
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