GRK6-IN-1 (Compound 18) is the inhibitor for G protein-coupled receptorkinase 6 ( GRK6 ) with an IC 50 of 3.8-8 nM. GRK6-IN-1 also inhibits GRK7 , GRK5 , GRK4 and GRK1 with IC 50 s of 6.4, 12, 22 and 52 nM, respectively. GRK6-IN-1 has the potential for the research of multiple myeloma.
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