GRK6/Aurora A-IN-1

Overview

GRK6/Aurora A-IN-1 is a dual inhibitor of G protein-coupled receptor kinase 6 ( GRK6 )/ Aurora A , with IC 50 values of 120 nM and 11 nM, respectively. GRK6 is a key kinase required for the survival of multiple myeloma (MM) cells. GRK6-IN-2 has the potential for research on multiple myeloma.

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK) | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-142817
• CAS No.: 2677786-27-3
• Molecular Formula: C21H21FN6
• Molecular Weight: 376.43
• Purity: 98.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source