KR-39038

Overview

KR-39038 is an orally active and potent GRK5 ( G protein-coupled receptor kinase 5) inhibitor, with an IC 50 of 0.02 μM. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research.

Application

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Product Information

• Catalog No.: HY-143248
• CAS No.: 2770300-35-9
• Molecular Formula: C24H32ClFN6O
• Molecular Weight: 475.00
• Purity: 99.68%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source