Topoisomerase II inhibitor 3

Overview

Topoisomerase II inhibitor 3 (Compound 6 h ) is a acridone derivatives, as well as a Type II DNA topoisomerase ( topo II ) inhibitor , as a topo IIα/β inhibitor with the value of IC 50 is 0.17 μM for topo IIα and the value of IC 50 is 0.23 μM for topo IIβ subtypes, caused obvious DNA damage, and induced apoptosis by triggering the loss of mitochondrial membrane potential.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-143279
• CAS No.: 99140-25-7
• Molecular Formula: C18H20N4O4
• Molecular Weight: 356.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source