MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC 50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC 50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8).
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