GPP78

Overview

GPP78 (CAY10618) is a potent Nampt inhibitor with an IC 50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion . GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC 50 of 3.8 nM by inducing autophagy . GPP78 has anti-cancer and anti-inflammatory effects.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Signaling Pathways > NAMPT | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-14374
• CAS No.: 1202580-59-3
• Molecular Formula: C27H29N5O
• Molecular Weight: 439.55
• Purity: 99.9%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source