Bcl-2-IN-4

Overview

Bcl-2-IN-4 is a potent, orally active and selective Bcl-2 inhibitor with an IC 50 of 1.5 nM. Bcl-2-IN-4 displays >200-fold selectivity over Bcl-xL (IC 50 of 411 nM). Bcl-2-IN-4 inhibits RS4; 11 cell proliferation with an IC 50 of 2.7 nM (WO2021180040A1; compound 2).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-143872
• CAS No.: 2703134-40-9
• Molecular Formula: C46H50ClN9O7S
• Molecular Weight: 908.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source