Casopitant mesylate

Overview

Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P ( HY-P0201 ). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4 . Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).

Application

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Product Information

• Catalog No.: HY-14405A
• CAS No.: 414910-30-8
• Molecular Formula: C31H39F7N4O5S
• Molecular Weight: 712.72
• Purity: 99.08%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.71 mg/mL (1.00 mM); Clear solution
• Availability: In-stock

Source

Original product source