CPI-455

Overview

CPI-455 is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.

Application

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Product Information

• Catalog No.: HY-100421
• CAS No.: 1628208-23-0
• Molecular Formula: C16H14N4O
• Molecular Weight: 278.31
• Purity: 98.17%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (8.98 mM); Clear solution
• Availability: In-stock

Source

Original product source