ALK5-IN-9

Overview

ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI ( ALK5 ). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC 50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease.

Application

Products | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-144437
• CAS No.: 2489611-06-3
• Molecular Formula: C29H35F3N6O3
• Molecular Weight: 572.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source