Plinabulin

Overview

Plinabulin (NPI-2358) is a vascular disrupting agen ( VDA ) against tubulin-depolymerizing with an IC 50 of 9.8 nM against HT-29 cells. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells.

Application

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Product Information

• Catalog No.: HY-14444
• CAS No.: 714272-27-2
• Molecular Formula: C19H20N4O2
• Molecular Weight: 336.39
• Purity: 98.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.43 mM); Clear solution
• Availability: In-stock

Source

Original product source