MEK/PI3K-IN-1

Overview

MEK/PI3K-IN-1 (compound 6r) is a potent MEK/PI3K inhibitor, with IC 50 values of 124 nM ( MEK1 ), 130 nM ( PI3Kα ), and 236 nM ( PI3Kδ ), respectively. MEK/PI3K-IN-1 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-1 shows anti-proliferative activity against tumor cell lines.

Application

Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > MEK | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > PERK

Product Information

• Catalog No.: HY-144692
• CAS No.: 2281803-28-7
• Molecular Formula: C36H37F5IN9O6
• Molecular Weight: 913.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source