FLT3/ITD-IN-2

Overview

FLT3/ITD-IN-2 (Compound 17) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 0.3, 0.4 and 1.0 nM against FLT3 D835Y , FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-2 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FLT3

Product Information

• Catalog No.: HY-144710
• CAS No.: 2489446-59-3
• Molecular Formula: C23H26F3N7O2
• Molecular Weight: 489.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source