FLT3/ITD-IN-3

Overview

FLT3/ITD-IN-3 (Compound 19) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 0.3, 0.4 and 0.9 nM against FLT3 D835Y , FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-3 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FLT3

Product Information

• Catalog No.: HY-144711
• CAS No.: 2489446-47-9
• Molecular Formula: C22H26ClN7O2
• Molecular Weight: 455.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source