L5-DA

Overview

L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC 50 =4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis , and cell cycle arrest.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > G-quadruplex | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-144712
• CAS No.: 2986876-41-7
• Molecular Formula: C32H34N6O2
• Molecular Weight: 534.65
• Purity: 99.03%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 1.25 mg/mL (2.34 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source