BRG1-IN-1

Overview

BRG1-IN-1 (Compound 11d) is a potent inhibitor of SMARCA4/BRG1 . BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-144720
• CAS No.: 2616813-99-9
• Molecular Formula: C20H19FN2O
• Molecular Weight: 322.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source