XPO1-IN-1

Overview

XPO1-IN-1 (compound D4) is an orally active and potent XPO1 inhibitor, with an IC 50 of 24 nM in MM.1S cell. XPO1-IN-1 can efficiently induce cell apoptosis and cell cycle arrest. XPO1-IN-1 displays favorable metabolic stability and pharmacokinetic properties. XPO1-IN-1 can be used for multiple myeloma (MM) research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-144763
• CAS No.: 3033267-42-1
• Molecular Formula: C20H15F6N5O3S
• Molecular Weight: 519.42
• Purity: 98.08%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.81 mM); Clear solution
• Availability: In-stock

Source

Original product source