NF-κB-IN-4

Overview

NF-κB-IN-4 (compound 17) is a potent NF-κB pathway inhibitor with blood brain barrier (BBB) permeability. NF-κB-IN-4 exhibits potential anti-neuroinflammatory activity with low toxicity. NF-κB-IN-4 can block the activation and phosphorylation of IκBα, reduce expression of NLRP3 , and thus inhibit NF-κB activation. NF-κB-IN-4 can be used for neuroinflammation related diseases research.

Application

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Product Information

• Catalog No.: HY-144765
• CAS No.: 3033258-60-2
• Molecular Formula: C18H15FN4O
• Molecular Weight: 322.34
• Purity: 98.51%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.76 mM); Suspended solution
• Availability: In-stock

Source

Original product source