AL-GDa62

Overview

AL-GDa62 is a derivative of the CDH1/E-cadherin modulator SLEC-11 ( HY-145268 ) and induces apoptosis in CDH1 -/- cells. AL-GDa62 has an EC 50 of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild type) and mutant MCF10A-CDH1 -/- , respectively. AL-GDa62 specifically inhibits TCOF1, ARPC5, and UBC9, and suppresses SUMOylation at low micromolar concentrations.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cadherin

Product Information

• Catalog No.: HY-145269
• CAS No.: 2761538-66-1
• Molecular Formula: C24H28FN3O
• Molecular Weight: 393.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source