IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC 50 s of 28 nM and 144 nM for IDO1 and IDO2 , respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO)
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