Clozapine dihydrochloride

Overview

Clozapine (HF 1854) dihydrochloride is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM).

Application

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Product Information

• Catalog No.: HY-14539B
• CAS No.: 2711603-38-0
• Molecular Formula: C18H21Cl3N4
• Molecular Weight: 399.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source