NU5455

Overview

NU5455 is a potent, selective, and orally active inhibitor of DNA-PKcs . NU5455 administration increases both the efficacy and the toxicity of a parenterally administered topoisomerase inhibitor . NU5455 enhances the activity of Doxorubicin released locally in liver tumor xenografts without inducing any adverse effect.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA-PK

Product Information

• Catalog No.: HY-145427
• CAS No.: 1257235-99-6
• Molecular Formula: C34H33N3O5S
• Molecular Weight: 595.71
• Purity: 98.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (8.39 mM); Clear solution
• Availability: In-stock

Source

Original product source