Zilurgisertib

Overview

Zilurgisertib (INCB-000928; NBU-928) is a selective ALK2 inhibitor with an IC 50 value of 15 nM. Zilurgisertib inhibits SMAD1/5 phosphorylation with an IC 50 value of 63 nM. Zilurgisertib inhibits hepcidin production and improve anemia. Zilurgisertib can be used in melanoma research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-145608
• CAS No.: 2173389-57-4
• Molecular Formula: C30H38N4O3
• Molecular Weight: 502.65
• Purity: 98.25%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (4.97 mM); Clear solution
• Availability: In-stock

Source

Original product source