MAP855

Overview

MAP855 is a highly potent, selective, ATP-competitive and orally active MEK1/2 kinase inhibitor ( MEK1 ERK2 cascade IC 50 =3 nM, pERK EC 50 =5 nM). MAP855 shows equipotent inhibition of wild-type and mutant MEK1/2.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > MEK | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-145702
• CAS No.: 1660107-77-6
• Molecular Formula: C28H23ClF2N6O3
• Molecular Weight: 564.97
• Purity: 98.37%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.43 mM); Clear solution
• Availability: In-stock

Source

Original product source