PR-104A

PR-104A
  • CAS No.:680199-06-8
  • Grade:98.98%
  • Formula:C14H19BrN4O9S
  • M.W.:499.29
  • Solvent:≥ 6.25 mg/mL (12.52 mM); Clear solution

Overview

PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity. PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL).

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA Alkylator/Crosslinker | Products > Signaling Pathways > Drug Metabolite

Product Information

  • Catalog No.: HY-14572
  • CAS No.: 680199-06-8
  • Molecular Formula: C14H19BrN4O9S
  • Molecular Weight: 499.29
  • Purity: 98.98%
  • Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
  • Solubility: ≥ 6.25 mg/mL (12.52 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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