EGFR-IN-45

Overview

EGFR-IN-45 is a potent epidermal growth factor receptor ( EGFR ) pan inhibitor, with IC 50 s of 0.4 µM and 1.6 µM for EGFR and CDK2 , respectively. EGFR-IN-45 also inhibit Topo I and Topo II . EGFR-IN-45 arrests cancer cells in the pre-G1 phase and induces apoptosis .

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-145867
• CAS No.: 2765560-03-8
• Molecular Formula: C28H23N7O
• Molecular Weight: 473.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source