PKN1/2-IN-1

Overview

PKN1/2-IN-1 is a potent cell permeabilizer and selective PKN1/2 inhibitor with IC 50 values of 16 nM and 210 nM for PKN1 and PKN2 , respectively, and K i values of 8 nM and 108 nM, respectively. PKN1/2-IN-1 exhibits strong intracellular PKN2 binding capacity in NanoBRET assays ( IC 50 = 2.1 μM). PKN1/2-IN-1 can be used to study physiological processes such as tumor cell migration.

Application

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Product Information

• Catalog No.: HY-145899
• CAS No.: 942425-34-5
• Molecular Formula: C14H15N3O
• Molecular Weight: 241.29
• Purity: 99.92%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source