Sirt1/2-IN-1

Overview

Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC 50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1 , SIRT2 and SIRT3 , respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC 50 of 32.05 µg/mL. Sirt1/2-IN-1 shows prominent anticancer activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > Microtubule/Tubulin

Product Information

• Catalog No.: HY-146013
• CAS No.: 2402779-21-7
• Molecular Formula: C22H13ClN2OS2
• Molecular Weight: 420.93
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source