NOD1/2 antagonist-1

Overview

NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding oligomerization domain-like receptor 1/2) dual antagonist, with IC 50 values of 1.13 ( NOD1 ) and 0.77 μM ( NOD2 ), respectively. NOD1/2 antagonist-1 has a acceptable T 1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-146034
• CAS No.: 2704623-69-6
• Molecular Formula: C32H28ClF5N4O4
• Molecular Weight: 663.03
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source