KRAS G12C inhibitor 48

Overview

KRAS G12C inhibitor 48 (compound 6e) is a potent KRAS G12C inhibitor with an IC 50 of 639.91 nM. KRAS G12C inhibitor 48 (0-50 µM) shows anti-proliferative activity with IC 50 s of 0.796, 6.33, 16.14 µM for H358, H23, A549 cells, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-146061
• CAS No.: 3033236-94-8
• Molecular Formula: C36H39ClN8O2
• Molecular Weight: 651.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source