α7 nAchR-JAK2-STAT3 agonist 1

Overview

α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC 50 value of 0.32 μM for nitric oxide (NO) . α7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS , IL-1β, and IL-6 in murine RAW264.7 macrophages. α7 nAchR-JAK2-STAT3 agonist 1 can inhibit LPS-induced NO release, NF-κB activation and cytokine production. α7 nAchR-JAK2-STAT3 can be used for researching sepsis.

Application

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Product Information

• Catalog No.: HY-146066
• CAS No.: 2108714-20-9
• Molecular Formula: C25H30O6
• Molecular Weight: 426.50
• Purity: 98.51%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.86 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source