EGFR-IN-55 (Compound 8a) is a potent EGFR inhibitor with IC 50 values of 70 nM and 3.9 nM against EGFR WT and EGFR L858R/T790M , respectively. EGFR-IN-55 arrests NCI-H1975 cells in G0/G1 phase and shows anticancer activity.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR
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