PI3K/HDAC-IN-2

Overview

PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC 50 s of 226 nM, 279 nM, 467 nM, 29 nM for PI3Kα , PI3Kβ , PI3Kγ , PI3Kδ , respectively, and IC 50 s of 1.3 nM, 3.4 nM, 972 nM, 17 nM, 12 nM for HDAC1 , HDAC2 , HDC4, HDAC6 , HDAC8 , respectively. PI3K/HDAC-IN-2 exhibits PI3Kδ and class I and IIb HDAC selectivity. PI3K/HDAC-IN-2 has remarkable anticancer effects.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-146159
• CAS No.: 2361418-65-5
• Molecular Formula: C23H23N7O4
• Molecular Weight: 461.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source