HSP90-IN-13

Overview

HSP90-IN-13 (compound 5k) is a highly potent HSP90 pan inhibitor with an IC 50 value of 25.07 nM. HSP90-IN-13 has multi-target activity against EGFR , VEGFR-2 and Topoisomerase-2. HSP90-IN-13 causes cell cycle arrest at G2/M phase and induces apoptosis of MCF-7 cells through mitochondrial-mediated pathway.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > HSP | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-146228
• CAS No.: 2446055-29-2
• Molecular Formula: C26H21N5O3S
• Molecular Weight: 483.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source