KRAS inhibitor-14

Overview

KRAS inhibitor-14 (compound 3-22) is a potent KRAS G12C inhibitor with an IC 50 of 0.249 µM. KRAS inhibitor-14 shows p-ERK inhibition activities with IC 50 s of 1.12, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-14 has the potential for the research of pancreatic, colorectal, and lung cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-146544
• CAS No.: 2230873-78-4
• Molecular Formula: C20H15Cl3FN3O2S
• Molecular Weight: 486.77
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source